Gene description for PSAP
Gene name	prosaposin
Gene symbol	PSAP
Other names/aliases	GLBA PARK24 PSAPD SAP1 SAP2
Species	Homo sapiens
Experiment description of studies that identified PSAP in Prostate cancer cells
1 Experiment ID 136 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry [QTOF]    Supporting data    MSS    PubMed ID 22723089    Organism Homo sapiens Experiment description Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Authors Hosseini-Beheshti E, Guns ES. Journal name MCP Publication year 2012 Sample Prostate cancer cells Sample name PC3 - Rep 2 Isolation/purification methods Sucrose density gradient Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [QTOF] EV-TRACK EV120018: EV-METRIC:38%
2 Experiment ID 137 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry [QTOF]    Supporting data    MSS    PubMed ID 22723089    Organism Homo sapiens Experiment description Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Authors Hosseini-Beheshti E, Guns ES. Journal name MCP Publication year 2012 Sample Prostate cancer cells Sample name PC3 - Rep 3 Isolation/purification methods Sucrose density gradient Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [QTOF] EV-TRACK EV120018: EV-METRIC:38%
3 Experiment ID 139 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry [QTOF]    Supporting data    MSS    PubMed ID 22723089    Organism Homo sapiens Experiment description Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Authors Hosseini-Beheshti E, Guns ES. Journal name MCP Publication year 2012 Sample Prostate cancer cells Sample name DU145 - Rep 3 Isolation/purification methods Sucrose density gradient Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [QTOF] EV-TRACK EV120018: EV-METRIC:38%
4 Experiment ID 963 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 25844599    Organism Homo sapiens Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Authors Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, UlléA, Yachnin J, Nilsson S, Panaretakis T. Journal name Oncotarget Publication year 2015 Sample Prostate cancer cells Sample name DU145 Tax-Sen Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.12-1.19 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV150027: EV-METRIC:11%, 56%